Background Publications

Christoph Schaniel, Priyanka Dhanan, Bin Hu, Yuguang Xiong, Teeya Raghunandan, David M. Gonzalez, Sunita L. D’Souza, Arjun Yadaw, Jens Hansen, Gomathi Jayaraman, Bino Mathew, Moara Machado, Seth Berger, Joseph Tripodi, Vesna Najfeld, Jalaj Garg, Marc Miller, Colleen Lynch, Katherine Michelis, Neelima Tangirala, Himali Weerahandi, David C. Thomas, Robert Sebra, Milind Mahajan, Eric Schadt, Dusica Vidovic, Stephan C Schürer, Joseph Goldfarb, Evren U. Azeloglu, Marc R. Birtwistle, Eric A. Sobie, Jason C. Kovacic, Nicole C. Dubois, Ravi Iyengar. A Library of Induced Pluripotent Stem Cells from Clinically Well-Characterized, Diverse Healthy Human Individuals. bioRxiv 2020.10.29.360909; doi: https://doi.org/10.1101/2020.10.29.360909

Zhao S, Nishimura T, Chen Y, Azeloglu EU, Gottesman O, Giannarelli C, Zafar MU, Benard L, Badimon JJ, Hajjar RJ, Goldfarb J, Iyengar R. Systems pharmacology of adverse event mitigation by drug combinations. Sci Transl Med. 2013 Oct 9;5(206):206ra140. doi: 10.1126/scitranslmed.3006548. PMID: 24107779

Zhao S, Iyengar R. Systems pharmacology: network analysis to identify multiscale mechanisms of drug action. Annu Rev Pharmacol Toxicol. 2012;52:505-21. doi: 10.1146/annurev-pharmtox-010611- 134520. Review. PMID:22235860

Berger SI, Iyengar R. Role of systems pharmacology in understanding drug adverse events. Wiley Interdiscip Rev Syst Biol Med. 2011 Mar-Apr;3(2):129-35. doi: 10.1002/wsbm.114. Epub 2010 Aug 27. Review. PMID: 20803507

Berger SI, Ma'ayan A, Iyengar R. Systems pharmacology of arrhythmias. Sci Signal. 2010 Apr 20;3(118):ra30. doi: 10.1126/scisignal.2000723. Erratum in: Sci Signal. 2010;3(121):er5. PMID: 20407125

Ma'ayan A, Jenkins SL, Goldfarb J, Iyengar R.Network analysis of FDA approved drugs and their targets. Mt Sinai J Med. 2007 Apr;74(1):27-32. PMID: 17516560